Year: 2012

AUTHORS
J.J. Vaquero
J.J. Sanchez
E. Lage
J.M. Udias
P. Guerra
M. Desco
JOURNAL IEEE Nuclear Science Symposium Conference Record, 2012
ABSTRACT
PET detector modules that implement depth of interaction information reduce uncertainties about the actual line-of-response after positron annihilation. This, in turn, has an effect in the spatial resolution and uniformity across the field of view of the reconstructed image. It also has an effect on the system sensitivity since it enables the use of thicker crystal with respect to a non-DOI system without deteriorating significantly the spatial resolution. In this work we evaluate a DOI detector design based on a scintillator phoswich of two types of pixelated crystals with different time decay constants. A matrix of silicon phomultipliers (SiPM) was coupled to this crystal array without any light-guide, and its outputs were connected to an anger logic type of charge divider which outputs were buffered using a transimpedance amplifier.

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AUTHORS
M Abella
E Vicente
A Rodrı́guez-Ruano
S España
E Lage
M Desco
J M Udias
J J Vaquero
JOURNAL Physics in Medicine & Biology, Vol 57,No 22, September 2012
ABSTRACT Technological advances have improved the assembly process of PET detectors, resulting in quite small mechanical tolerances. However, in high-spatial-resolution systems, even submillimetric misalignments of the detectors may lead to a notable degradation of image resolution and artifacts. Therefore, the exact characterization of misalignments is critical for optimum reconstruction quality in such systems. This subject has been widely studied for CT and SPECT scanners based on cone beam geometry, but this is not the case for PET tomographs based on rotating planar detectors. The purpose of this work is to analyze misalignment effects in these systems and to propose a robust and easy-to-implement protocol for geometric characterization. The result of the proposed calibration method, which requires no more than a simple calibration phantom, can then be used to generate a correct 3D-sinogram from the acquired list mode data.
LINK http://iopscience.iop.org
AUTHORS
G. Tapias
J. L. Villena
R. Kreuger
E. Lage
F. J. Beekman
JOURNAL IEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 59, NO. 3, JUNE 2012
ABSTRACT We have developed an 80-channel readout system for gamma cameras which acquires PMT signals and stores them in list-mode format on a computer. The system combines low noise and a large signal range to handle PMT signals from a wide range of SPECT and PET tracers simultaneously (27 to 511 keV).

All channels of the read-out system have a gated integrator to determine the charge per event. Each 16 channels are multiplexed to a 12-bit 40 MS/s pipelined ADCs. Using multiplexing only 5 ADCs are needed which share a commercial USB 2.0 interface board to send the event data to the computer.

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AUTHORS
J.J. Sánchez
A. Olmo
E. Lage
M. Desco
J.J. Vaquero
JOURNAL XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica, 2012
ABSTRACT
Se presenta el proceso de diseño y caracterización de un detector para un nuevo tomógrafo SPECT para animales de laboratorio. El fSPECT es un tomógrafo de bajo coste pero con prestaciones suficientes para gran parte de los estudios que se realizan en un laboratorio de investigación. El sistema se basa en dos detectores con cristal de centelleo de CsI(Na) acoplados a un tubo fotomultiplicador sensible a posición. En este trabajo se presentan los sistemas electrónicos de los detectores y los resultados de caracterización de los parámetros intrínsecos del detector.
LINK https://researchportal.uc3m.es
AUTHORS
A. Sisniega
M. Abella
E. Lage
M. Desco
J.J. Vaquero
JOURNAL IEEE Nuclear Science Symposium Conference Record, 2012
ABSTRACT
Scattered photons highly degrade the quality of X-ray images and their effect has become more important due to the increasing interest in cone-beam geometry for the acquisition of CT (CBCT) and micro-CT data. The random nature of scatter events and the great influence of the sample suggest that the most accurate methods for their estimation are Monte Carlo (MC) techniques, but their use is usually hampered by the large computation time required to obtain an acceptable estimation of the scattered radiation. We present an approach for scatter correction in CBCT by MC estimation, speeding up the computation by means of general purpose graphic processing units (GPGPU) and developing a framework for the automatic correction and reconstruction of projection data.

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AUTHORS
Andrew L. Goertzen
Qinan Bao
Mélanie Bergeron
Eric Blankemeyer
Stephan Blinder
Mario Cañadas
Arion F. Chatziioannou
Katherine Dinelle
Esmat Elhami
Hans-Sonke Jans
Eduardo Lage
Roger Lecomte
Vesna Sossi
Suleman Surti
Yuan-Chuan Tai
Juan José VaqueroEsther Vicente
Darin A. Williams
Richard Laforest
JOURNAL Journal of Nuclear Medicine, vol. 53, n. 8, aug. 2012. Pp. 1-10
ABSTRACT PurposeThe National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for performance measurements of small-animal tomographs was recently published. Before this standard, there were no standard testing procedures for preclinical PET systems, and manufacturers could not provide clear specifications similar to those available for clinical systems under NEMA NU 2-1994 and 2-2001. Consequently, performance evaluation papers used methods that were modified adhoc from the clinical PET NEMA standard, thus making comparisons between systems difficult.

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Funding Agency

Comunidad de Madrid, Madrid – MIT M+Vision Consortium

Principal Investigator/s

Dr. Eduardo Lage and Dr. Joaquín L. Herraiz, E. Addalsteinson (Consortium PI)

Information Type of Grant: Competitive funding , United states/ Comunidad de Madrid

Grant code: —

Awardee Organization: MIT, Brigham & Women’s Hospital, CNIO, Gregorio Maranon Hospital

Project Start Date: January 2012

Project End Date: June 2014

Total Funding: 250,000 €

MEDIC Personnel included in the grant / Role: Dr.Eduardo Lage / PI

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Funding Agency

Comunidad de Madrid, Madrid – MIT M+Vision Consortium

Principal Investigator/s

 Daryl Lim, Nicholas J. Durr, E. Lage, E. Addalsteinson (Consortium PI)

Information Type of Grant: Competitive funding , United states/Comunidad de Madrid

Grant code: —

Awardee Organization: MIT, New England College of Optometry, CSIC

Public Health Relevance Statement: —

Project Start Date: January 2012

Project End Date: June 2014

Total Funding: 300,000 €

MEDIC Personnel included in the grant / Role: Dr. Eduardo Lage / Investigator / Technical Responsible

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Contact Us

eduardo.lage@uam.es
+34 91 497-5787

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