System and Method to improve image quality of Emission Tomography when using advanced radionuclides

AUTHORS
 Eduardo M. Lage
Joaquin L. Herraiz
Vicente J. Parot
Shivang R. Dave
APPLICATION NUMBER
PCT/US2014/045220
PUBLICATION DATE January 15th, 2015
ABSTRACT A method and system for acquiring a series of medical images includes a plurality of detectors configured to be arranged to acquire gamma rays emitted from a subject as a result of an advanced radionuclide administered to the subject and communicate signals corresponding to acquired gamma rays. A data processing system is configured to receive the signals from the plurality of detectors, determine double coincidence event dataset and a multiple coincidence event dataset, separate the multiple coincidence event dataset into at least one of a standard lines of response dataset and a nonstandard lines of response dataset, and apply a background correction to the double coincidence event dataset based on the non-standard lines of response dataset and/or the standard lines of response dataset to obtain a standard coincidence dataset.
LINK https://patentscope.wipo.int

Apparatus and method of determining an eye prescription

AUTHORS
Nicholas J. Durr
Eduardo Lage
Shivang Dave
APPLICATION NUMBER PCT/US2014/045305
PUBLICATION DATE 8 January 2015
ABSTRACT Eye prescriptions may be determined by providing a simple, easy to use, portable device with a specially configured targeting light source that aligns the eye, mitigates accommodation, and provides accurate results. Unlike stationary, closed view autorefractors, this device typically is portable, self-usable, relatively inexpensive, enabling more widespread use across the world.
LINK https://worldwide.espacenet.com

Inter-detector scatter enhanced emission tomography

AUTHORS
 Eduardo Lage
Joaquin Herraiz
Vicente Parot
Shivang Dave
APPLICATION NUMBER PCT/US2013/068858
PUBLICATION DATE May 15th, 2014
ABSTRACT A method and system for acquiring a series of medical images includes receiving medical imaging data corresponding to photons emitted from a subject having received a dose of a radiotracer. Determining, from the medical imaging data, coincidence events including photon coincidence events involving two photons and photon coincidence events involving more than two photons. The photon coincidence events involving two photons and photon coincidence events involving more than two photons are processed and use to reconstruct a series of medical images of the subject.
LINK https://patentscope.wipo.int

Method and device for detecting and differentiating valid events in Gamma Radiation Detectors

AUTHORS
 LAGE NEGRO, Eduardo (ES); 
TAPIAS GIL, Gustavo (ES);
SÁNCHEZ GONZÁLEZ, José Antonio (ES);
DEL PINO VAQUERO, Javier (ES);
VAQUERO LÓPEZ, Juan José (ES);
DESCO MENÉNDEZ, Manuel (ES);
APPLICATION NUMBER PCT/ES2009/070456
PUBLICATION DATE 14 August 2013
ABSTRACT Method for detecting and differentiating valid events in gamma radiation detectors (505, 510), which method comprises the following steps of: obtaining a timing pulse from the detector (505, 510) in which an event is detected comparing the timing pulse obtained with two thresholds (U1, U2), thus generating two digital comparison pulses, the input edges of which correspond to the instants at which the timing pulse exceeds said thresholds (U1, U2) combining the two digital comparison pulses such that a digital window pulse is generated, the duration of which is Tpulse =TA +- TB, where TA is a fixed value and TB is the interval of time which has elapsed between the respective input edges of the digital comparison pulses and determining whether the event is valid as a function of the digital window pulse obtained.
LINK https://worldwide.espacenet.com

Apparatus and method of determining an eye prescription

AUTHORS
Nicholas J. Durr
Eduardo Lage
Shivang Dave
DAryl Lim
Susana Marcos
Carlos Dorronsoro
APPLICATION NUMBER PCT/US2014/045261
PUBLICATION DATE 8 January 2015
ABSTRACT Purpose. To introduce a novel autorefractor design that is intended to be manufacturable at low cost and evaluate its performance in measuring refractive errors. Methods. We developed a handheld, open-view autorefractor (the ͚͚QuickSee͛͛ [QS]) that uses a simplified approach to wavefront sensing that forgoes moving parts and expensive components

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Normalization Correction for Multiple-Detection Enganced Emission Tomography

AUTHORS
 Eduardo Lage
Joaquin Herraiz
Vicente Parot
Shivang Dave
APPLICATION NUMBER
PCT/US2014/043826
PUBLICATION DATE December 31st, 2014
ABSTRACT A method and system for acquiring a series of medical images includes acquiring imaging data, identifying double coincidence events and multiple detection (MD) coincidence events from the imaging data, and storing the double coincidence events and the MD coincidence events in a first dataset and a second dataset, respectively. The method also includes applying a normalization correction to the first dataset and/or the second dataset using normalization values based on double coincidence events and/or MD coincidence events to obtain at least one normalized dataset, and reconstructing a series of medical images of the subject from the at least one normalized dataset.
LINK https://patentscope.wipo.int

Multiplexable Emission Tomography

AUTHORS
 Eduardo Lage
Joaquin Herraiz
Vicente Parot
APPLICATION NUMBER
PCT/US2013/038846
PUBLICATION DATE December 19th, 2013
ABSTRACT A method and system for acquiring a series of medical images during a common imaging process, includes a plurality of detectors configured to be arranged to acquire gamma rays emitted from a subject as a result of multiple radiotracers administered to the subject and communicate signals corresponding to acquired gamma rays. A data processing system is configured to receive the signals from the plurality of detectors and identify temporal information and energy information of photons of the acquired gamma rays. A reconstruction system is configured to receive the signals, the temporal information, and the energy information from the data processing system and reconstruct therefrom a series of medical images of the subject, wherein at least one of the images in the series of medical images corresponds to only to information acquired from gamma rays emitted as a result of a given one of the multiple radiotracers.
LINK https://patentscope.wipo.int

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